A review of 3D image-based dosimetry, technical considerations and emerging perspectives in 90Y microsphere therapy
Yttrium-90 radioembolization is a well-established therapy for the treatment of hepatocellular carcinoma.
Post-therapy scintigraphy, also known as radionuclide scintigraphy, is an important diagnostic tool used in the medical field, particularly in the realms of nuclear medicine and endocrinology. This imaging technique is especially valuable in assessing the efficacy of therapeutic interventions, monitoring disease progression, and evaluating the function of various organs and tissues.
The procedure involves the administration of a radioactive isotope, typically through injection, ingestion, or inhalation. This isotope acts as a tracer, and its distribution and uptake within the body are imaged using a gamma camera. The resulting images provide clinicians with detailed insights into the body’s physiological processes and molecular functions, which are often not visible through other imaging modalities such as MRI or CT scans.
One of the most common applications of post-therapy scintigraphy is in the treatment of thyroid disorders, particularly thyroid cancer. After a patient undergoes radioiodine therapy, post-therapy scintigraphy is performed to determine the effectiveness of the treatment. It helps identify residual thyroid tissue, detect metastatic disease, and assess the body’s response to the administered radioactive iodine. The images captured can pinpoint areas where there is an abnormal accumulation of the radioactive substance, indicating potential issues that require further medical attention.
Another key application of this technique is in the field of oncology, where it is used to monitor tumour response to therapy. For instance, bone scintigraphy can assess the impact of treatments on bone metastases, a common complication in cancers such as prostate and breast cancer. By evaluating the uptake of radioisotopes in bone tissue, doctors can determine whether the cancer has spread or how it is responding to treatment.
The advantage of post-therapy scintigraphy over other imaging techniques lies in its ability to provide functional information about the body. This makes it an invaluable tool in the diagnosis and management of diseases. It is highly sensitive and can detect abnormalities at an early stage, thereby facilitating timely medical interventions.
Even though it has numerous benefits, post-therapy scintigraphy does come with potential risks, primarily related to radiation exposure. However, the amount of radiation used is generally low and is considered safe for most patients. Healthcare providers always weigh the benefits of the scan against the potential risks to ensure the safety of the patients.
In conclusion, post-therapy scintigraphy is a sophisticated diagnostic approach that plays a critical role in modern medicine. Its ability to provide a deep understanding of bodily functions at a molecular level is unparalleled, making it an essential component of patient care in numerous medical specialties.
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Yttrium-90 radioembolization is a well-established therapy for the treatment of hepatocellular carcinoma.